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Debio 9902 - ZT-1
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Date Item Title
22-Apr-2006 Population Pharmacokinetics of ZT-1 and its active Metabolite Huperzine A after i.v., oral and s.c. Administration in Healthy Volunteers
22-Apr-2006 ZT-1 for the Symptomatic Treatment of Mild to Moderate Alzheimer´s Disease: Preliminary Results of a Multicenter, Randomised, Double-blind Placebo and Active controlled Phase II Study
22-Apr-2006 Preparation of a sustained-release Implant of the Acetylcholinesterase Inhibitor ZT-1 by Hot-Melt Extrusion (HME) and Evaluation in Rats
22-Apr-2006 Reversal of Scopolamine-Related Deficits in Cognitive Functions by ZT-1, A Huperzine-A Derivative
22-Apr-2006 The Prolonged Action of the Acethylcholinesterae Inhibitor ZT-1 after s.c. Injections of Sustained Release Implants in Healthy Volunteers
29-Jun-2004 The Effectiveness of ZT-1 and Donepezil in Reversing Scopolamine-induced Cognitive Impariment in Elderly Volunteers
27-Nov-2003 The sustained release of the acetylcholinesterase inhibitor ZT-1 confers the potential for a more efficient neuroprotection in rats
05-Jun-2003 The Psychopharmacology of Huperzine A: an Alkaloid with Cognitive Enhancing and Neuroprotective Properties of Interest in the Treatment of Alzheimer´s Disease
 
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