Open-label, non-randomized, exploratory pre-operative window-of-opportunity trial to investigate the pharmacokinetics and pharmacodynamics of the smac mimetic Debio 1143 in patients with resectable squamous cell carcinoma of the head and neck

Presented at AACR 2019, Atlanta, GA, US

C Gomez-Roca^a, C Even^b, C Le Tourneau^c, N Basté Rotllan^b, JP Delord^a, J Sarini^a, S Vergez^a, S Temam^b, C Hoffmann^c, P Rochaix^a, B Gavillet^d, E Rouits^d, C Barcelo^d, A Ménétrey^d, F Brichory^d, D Rechavi-Robinson^d, V Bize^d, S del Rizzo^d, D Purcea^d, S Brienza^d, C Zanna^d, G Vuagniaux^d and S Szyldergemajn^d

^aInstitut Universitaire du Cancer de Toulouse – Oncopole, Toulouse, France,
^bInstitut Gustave-Roussy, Villejuif, France,
^cInstitut Curie, Paris, France,
^dDebiopharm International SA, Lausanne, Switzerland