Publications

The cyclophilin inhibitor alisporivir prevents hepatitis C virus–mediated mitochondrial dysfunction

Debio-025 is more effective than prednisone in reducing muscular pathology in mdx mice

HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors.

Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment

Debio-025 inhibits HIV-1 by interfering with an early event in the replication cycle

Cyclosporine A inhibits hepatitis C virus nonstructural protein 2 through cyclophilin A.

Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics

The cyclophilin inhibitor Debio 025 normalizes mitochondrial function, muslce apoptosis and ultrastructural defects in Col6a1-/- mypathic mice

The Cyclophilin Inhibitor Debio 025 Combined with PEG IFNα2a Significantly Reduces Viral Load in Teatment-Naïve Hepatitis C Patients