Publications
Evaluation of the microbiota-sparing properties of the anti-staphylococcal antibiotic afabicin
Pharmacokinetic-pharmacodynamic modelling of afabicin in vitro activity against Staphylococcus aureus
Antimicrobial activity of the new FabI inhibitor Afabicin desphosphono against intraosteoblastic Staphylococcus aureus
Afabicin, a first-in-class anti-staphylococcal antibiotic, in the treatment of acute bacterial skin and skin structure infections: clinical non-inferiority to vancomycin/linezolid
Staphylococcal-selective antibiotic afabicin preserves the human gut microbiota
The Staphylococcal-specific Antibiotic Debio 1450 Minimizes Disturbance to the Gut Microbiota in Mice
Activity of the novel Fabl inhibitor Debio 1452 against intracellular forms of susceptible and resistant S. aureus: comparison with linezolid,…
Single Dose Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of a FabI Inhibitor, the Prodrug Debio 1450 and…
Safety, tolerability and pharmacokinetics of AFN–1252 administered as immediate release tablets in healthy subjects