Publications

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April 28, 2025

The WEE1 inhibitor Debio 0123 is synergistic with the PKMYT1 inhibitor lunresertib in preclinical models of ovarian and breast cancer

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April 25, 2025

Biology-driven, machine learning-based development of a biomarker to predict response to WEE1 inhibitor Debio 0123

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February 7, 2025

Cancer target back in contention with more selective inhibitor

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December 14, 2024

Site-selective template-directed synthesis of antibody Fc conjugates with concomitant ligand release

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October 14, 2024

The First-in-Class Anti-Staphylococcal Antibiotic Afabicin Desphosphono is Not Associated With Clostridioides difficile Infection in an in vitro Human Gut Model

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October 14, 2024

Assessment of Pharmacokinetic-Pharmacodynamic (PK-PD) Target Attainment for the Anti-Staphylococcal Antibiotic Afabicin

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October 14, 2024

Results from A Phase 2 Clinical Trial for Treatment of Bone And Joint Infections with Afabicin, A First-in-Class Selective Anti-Staphylococcal…

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September 13, 2024

Debio 0123 + Carboplatin for Patients with Advanced Solid Tumors: Safety, Preliminary Efficacy and Determination of Recommended Phase 2 Dose

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September 13, 2024

Debio 0123, a highly selective WEE1 inhibitor, combined with carboplatin and etoposide in patients with small cell lung cancer that…

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