Publications

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June 9, 2023

Evaluation of the microbiota-sparing properties of the anti-staphylococcal antibiotic afabicin

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April 17, 2023

Pharmacokinetic-pharmacodynamic modelling of afabicin in vitro activity against Staphylococcus aureus

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March 18, 2021

Antimicrobial activity of the new FabI inhibitor Afabicin desphosphono against intraosteoblastic Staphylococcus aureus

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August 3, 2020

Afabicin, a first-in-class anti-staphylococcal antibiotic, in the treatment of acute bacterial skin and skin structure infections: clinical non-inferiority to vancomycin/linezolid

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April 21, 2018

Staphylococcal-selective antibiotic afabicin preserves the human gut microbiota

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October 29, 2016

The Staphylococcal-specific Antibiotic Debio 1450 Minimizes Disturbance to the Gut Microbiota in Mice

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April 11, 2016

Activity of the novel Fabl inhibitor Debio 1452 against intracellular forms of susceptible and resistant S. aureus: comparison with linezolid,…

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September 19, 2015

Single Dose Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of a FabI Inhibitor, the Prodrug Debio 1450 and…

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September 11, 2015

Safety, tolerability and pharmacokinetics of AFN–1252 administered as immediate release tablets in healthy subjects

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